Clomid vs Letrozole
Clomid vs Letrozole
Clomid and Letrozole are compared here on the things that actually differ between them: what class each belongs to, what each acts on, how each is supplied and what each costs per milligram. Where the registry has no figure for one of them the row is left out rather than filled in.
Reference only. This page covers what the compound is, how it is presented and how it is handled. It does not give dosing protocols or administration schedules, and it is not medical advice.
Side by side
| Clomid | Letrozole | |
|---|---|---|
| Class | Selective oestrogen receptor modulator (SERM) | Non-steroidal aromatase inhibitor |
| Acts on | A SERM comprising two isomers, enclomiphene and zuclomiphene, with differing half-lives and receptor behaviour. Raises gonadotropin output by blocking hypothalamic oestrogen feedback. | A reversible competitive aromatase inhibitor, the most potent of the non-steroidal class in published suppression comparisons. |
| Supplied as | Oral tablet. | Oral tablet. |
| Half-life | Mixed: the zuclomiphene isomer persists far longer than enclomiphene, which is why washout is prolonged. | Approximately 2 days. |
| Storage | Cool, dry, dark. | Cool, dry, dark. |
| Listings | 1 | 1 |
| Price from | £22 | £25 |
What actually differs
The clearest difference is class: Clomid is a selective oestrogen receptor modulator (SERM), Letrozole is a Non-steroidal aromatase inhibitor. Half-life differs as well: Mixed: the zuclomiphene isomer persists far longer than enclomiphene, which is why washout is prolonged for Clomid against Approximately 2 days for Letrozole.
Stocked at The PED Shop
Clomid - PHARMAin stock£22
Letrozole - Pharmaout of stock£25
Availability checked 2026-09-09. The product page carries live stock.